罗红霉素盐酸氨溴索片英文说明书

罗红霉素盐酸氨溴索片英文说明书ROXISARA AM Composition : Each tablet of Roxisara AM contains roxithromycin 150 mg an

罗红霉素盐酸氨溴索片英文说明书 ROXISARAAM Composition:EachtabletofRoxisaraAMcontainsroxithromycin150 mgandambroxolhydrochloride30mg. Description: Roxithromycinisasemisynthetic,long-acting,acid-stablemacrolide antibiotic.Ascomparedtoerythromycin,ithasaverysimilar antibacterialspectrumofaction,betterbioavailabilitybytheoral route,bettertissuepenetration,andmuchlongerdurationofaction. ChemicallyitisdesignatedasErythromycin9-{0-[(2-methoxyethoxyl) methyl]oxime}(C41H76N2O15=837.0). Ambroxolisanactivemetaboliteofbromhexineandhassimilarbut somewhatlonger-lastingmucolyticaction.Chemicallyambroxol(as hydrochloridesalt)isdesignatedastrans-4-(2-Amino-3,5 dibromobenzylamino)cyclohexanolhydrochloride (C13H18Br2N2O1HCl=414.6).Ithasbeenincorporatedintablet RoxisaraAMtofacilitatebetterpenetrationofroxithromycininto respiratorytractfluidsforsuperiorantibacterialaction. PharmacologicalActionsandTheirMechanisms: RoxithromycinishighlyactiveagainstStreptococcuspyogenesandS. pneumoniae,Staphylococcusaureus(methicillin-sensitive)*,Clostridia, Corynebacteriumdiphtheriae,Bacillusanthracis,Erysipelothrix rhusiopathy,Listeriamonocytogenes,Propionibacteriumacnes,andalso