槲皮素对慢性肾脏疾病的影响

槲皮素对慢性肾脏疾病的影响 摘要:慢性肾脏病的发病率在我国和全球都呈逐年增高的趋势,已经成为一个全人类面临的重大公共卫生问题。研究表明槲皮素可通过降低血糖、抗氧化应激、抗炎及抑制肾脏纤维化等机制对肾脏

槲皮素对慢性肾脏疾病的影响 摘要:慢性肾脏病的发病率在我国和全球都呈逐年增高的趋势,已经成为一个 全人类面临的重大公共卫生问题。研究表明槲皮素可通过降低血糖、抗氧化应激、 抗炎及抑制肾脏纤维化等机制对肾脏起保护作用。本文旨在通过对其相关研究进行 综述,为慢性肾脏疾病的防治提供一定的临床思路。 关键词:槲皮素;慢性肾脏病;降血糖;抗氧化刺激;抗炎;纤维化 Quercetin on development of Chronic kidney disease YUAN Haobin, DAI Enlai, MA Li, ZHAO Li Abstract:The incidence of chronic renal disease in our country and the world is increasing year by year. It has become amajor public health problem facing all mankind. Considerable data have indicated that quercetin treatment caused areductionin glycemia, ameliorated inflammationoxidative stress and fibrosis, there is protection of kidney. The purpose of this paper is to provide aclinical thinking for the prevention and treatment of chronic kidney diseases through areview of related studies. Keywords:quercetin; Chronic kidney disease; hypoglycemic; antioxidant stimulation; Anti-inflammatory; fibrosis. 慢性肾脏病(Chronic kidney disease,CKD)是大多数肾脏疾病的统称,具有发 病率高、发现率低、合并症多、病程漫长、治疗成本高、致残率和致死率高等特 点。据有关流行病学调查[1],CKD的发病率在我国和全球都呈逐年增高的趋势,已