加拿大奶牛肉牛炭疽病

炭疽病 AnthraxPrepared by: Dr. Terry Hunt Translated by Dr. Fu Xiaoping 病因/发病机理 Cause & Pathogenesis炭疽杆

Anthrax 炭疽病 Preparedby:Dr.TerryHunt Cause&Pathogenesis TranslatedbyDr.FuXiaoping 病因/发病机理 炭疽杆菌引起的高度致死性败血症 Bacillusanthracis Highlyfatalsepticemiacausedby Largegram-positiveencapsulatedboxcarlikerod . 大革蓝氏杆菌 OIEReportableListBdisease OIEB 公众健康一通过呼吸、 列为类疾病 皮肤接触、摄取途径感染 PublicHealthconcerns transmissibletohumansbyingestion,cutaneouscontactor 一 inhalation(severalformsdependingonrouteofinfection) • 世界范围、在热带、血热带地区以土源性病原体常见 Worldwide,soilborneorganismmorecommonintropicsandsub-tropics Surviveswellinalkalinesoils • 可在碱性土壤中存活 100% • 发病率不等，死亡率约 Morbidityisvariablebutcasemortalityrate~100% • 所有动物均易感一牛、绵羊〉山羊、马、猪 Allspeciesaresusceptible-cattle&sheep>goats,horses&pigs •」 传播途径主要为摄取、呼吸、皮肤食触 Mainsourceoftransmissionisingestionbutcanalsobebyinhalation&cutaneous penetration • 发病动物排泄物、感染的尸体解剖、摄取感染死亡的动物或副产品 (皮革、毛、肉、骨粉) Transmittedbysickanimaldischarges,openinginfectedcarcasses,ingestionof infecteddeadanimalsorby-products(hides,wool,meat&bonemeal) 危险因素 • 流行地区水涝 RiskFactors • 干旱后出现水灾 Heavyrainfallinendemicareas Floodingproceededbydrought Opening • 解剖因炭疽病死亡的动物 ClinicalFindings carcassofanimalsdieingofAnthrax 临床症状 ・ 13 Incubationperiodof1-3weeks • 潜伏期周 Mostcommonly,animalsarefoundsuddenlydead • 多数常见动物突然死亡 Ifseenalive,hightemperature • iWj 体温 • 严重萎靡、无食欲、瘤胃静止、产量下降 Severedepression,anorexia,rumenstasisanddropinmilkproduction