杏鲍菇多糖提取及其颗粒剂制备工艺研究

杏鲍菇多糖提取及其颗粒剂制备工艺研究摘要：杏鲍菇是一种非常重要的食用菌，具有丰富的营养价值和药用价值。其中，多糖是其重要活性成分之一，被广泛研究和应用。本文以杏鲍菇为原料，采用水提醇沉法进行多糖提取，

杏鲍菇多糖提取及其颗粒剂制备工艺研究 摘要： 杏鲍菇是一种非常重要的食用菌，具有丰富的营养价值和药用价 值。其中，多糖是其重要活性成分之一，被广泛研究和应用。本文以杏 鲍菇为原料，采用水提醇沉法进行多糖提取，然后利用凝胶层析技术进 一步纯化，并最终制备成颗粒剂。研究结果表明，经硫酸熏蒸预处理 14.2% 后，杏鲍菇中多糖的提取率达到了；经凝胶层析后，多糖的纯度 90.8% 达到了；制备的颗粒剂经过质量评价和稳定性评估后具有良好的 物理化学性质和稳定性，适合应用于药品和保健食品行业。 关键词：杏鲍菇；多糖；提取；凝胶层析；颗粒剂 Abstract ： Pleurotus eryngii is an important edible mushroom with rich nutritional and medicinal value. Polysaccharides are one of its important active components, which have been widely studied and applied. In this study, water extraction and alcohol precipitation method were used to extract polysaccharides from P. eryngii, followed by further purification by gel chromatography, and finally prepared into granules. The results showed that the extraction rate of polysaccharides from P. eryngii reached 14.2% after sulfuric acid fumigation pretreatment; after gel chromatography, the purity of polysaccharides reached 90.8%. The prepared granules had good physical and chemical properties and stability after quality evaluation and stability evaluation, which were suitable for application in the pharmaceutical and health food industries. Keywords: Pleurotus eryngii; polysaccharide; extraction; gel chromatography; granules 一、前言 近年来，随着人们生活水平的不断提高和健康意识的逐渐增强，食 品和药品市场对于天然、绿色、高效的保健品和药物需求不断扩大，其 Pleurotus 中，植物和食用菌等天然资源成为人们研究的热点。杏鲍菇（ eryngii ）是一种重要的食用菌，具有高蛋白、低脂肪、低热量、高营