麒麟丸联合左氧氟沙星治疗伴有附性腺感染的弱精子症的临床疗效观察

麒麟丸联合左氧氟沙星治疗伴有附性腺感染的弱精子症的临床疗效观察高勇I，邓春华2(1.中山大学附属第一医院 生殖医学科,广州，510080； 2.中山大学附属第一医院 泌尿外科，广州，510080)

麒麟丸联合左氧氟沙星治疗伴有附性腺感 染的弱精子症的临床疗效观察 高勇邓春华 I2 ， 中山大学附属第一医院生殖医学科,广州，中山大学附属第一医院泌尿外 1.5100802. (； 科，广州，摘要：目的：观察麒麟丸联合左氧氟沙星治疗伴有附性腺感染的弱箱子症的疗效。方法： 510080) 将伴冇慢性附睾炎的弱粕子症患者例随机分为组，每组例患者。号组患者口服麒麟丸和左氧氟沙 1203401 星，号纽•患者口服麒麟丸，号组患者口服左氧氟沙星。每纟治疗个疗程：麒麟丸用法为每次次 23fl16g,3 /天，服用天；左氧氟沙星用法为每次次/犬，服用天。每组在治疗前和治疗个疗程后做精液 300.5g,1201 分析，以前向运动精子百分率和精液中过氧化物酶阳性的白细胞数为主要疗效指标，评价治疗效果。结果：入 选患者均完成了个疗程的治疗，与治疗前相比，个纽患者的前向运动精了百分率和精液中过氧化物酶阳性 13 的白细胞数均有显著改善。个治疗组在治疗后,前向运动粘子百分率的治疗有效率分别为、 PV0.05)360% ( 和精液中过氧化物酶阳性的白细胞数的治疗有效率分别为、和。结论：治 32.5%17.5%87.5%12.5%82.5% ： 疗伴有附性腺感染的弱精子症，麒麟丸联合左氧氟沙星可以明显提高椿子活动力，联合应用比单独应用上述药 物的具右更好的疗效，未见明显不良反应。 关键词：泌尿外科；弱精子症;附性腺感染；不育;麒麟丸；左氧氟沙星中图分类号： R321.1 QilinPillsandlevofloxacinforasthenospermiaassociated withinfectionofaccessorysexgland:Aclinicalobservation GAOYongi,DENGChunhua? (1.ReproductiveMedicinedepartment,TheFirstAffiliatedHospitalofSunYat-sen University,Guangzhou,510080; 2.Urologydepartment,TheFirstAffiliatedHospitalofSunYat-sen University,Guangzhou,510080) Abstract: Objective:ToobservetheefficacyofQilinPillsandlevofloxacininthetreatmentofasthenospermia associatedwithinfectionofaccessorysexglandMethods:Weconductedaclinicaltrialbyincluding120 ・ asthenospermiaassociatedwithinfectionofaccessorysexglandpatients,whowererandomlydividedinto3 groupsof40patients.Thepatientsinthegroup1weretreatedwithQilinPillsandlevofloxacin,inthegroup2 weretreatedwithQilinPillsandinthegroup3weretreatedwithlevofloxacin.Eachgroupgotonecourseof treatment:QilinPillsatthedoseof6gtidtor30days,andlevofloxacinatthedoseof0.5gqdtor20daysThen ・ weevaluatedtheclinicaleffectsoftreatmentwithspermparameters,includingthepercentageofprogressive motilityspermandperoxidase-positivewhitebloodcellcountinsemen.Results:Atotalof120patientsinthree groupsaccomplishedtheclinicaltrial.Comparedwiththebaseline,significantimprovementwasobservedinthese 2semenparametersafteronecourseoftreatmentinallthethreegroups(P<0.05)Inthepercentageof ・ progressivemotilitysperm,thetreatmentefficiencyofthesethreegroupswere60%,32.5%and17.5%;andin peroxidase-positivewhitebloodcellcountinsemen,thetreatmentefficiencyofthesethreegroupswere87.5%, 12.5%and82.5%Conclusion:QilinPillsandlevofloxacincanevidentlyimprovethespermmotilityof ・ H(20100171110060): 基金项：教育部高等学校博士学科点专项科研基金教育部高等学校博士学科点专项科研基金 (20130171120078) (1981-), gaoyong9971@163.com 作者简介：高勇男,副教授,主要研究方向:男性不育和性功能障碍. asthenospermia associatedwithinactionofaccessorysexglandpatientswithnoobviousadverseeventsThecombinationof ・ QilinPillsandlevofloxacinhadbettertreatmentefficiencythantheapplicationofthesedrugsalone. Keywords: Urology;Asthenospermia;Infectionofaccessorysexgland;Infertility;QilinPills;levofloxacin 引言 0